Hoping to make a tiny difference in this complicated mess. If you want to do so in a more concrete way in the U.S., have a look at the Resistance Manual

I have not been endorsed by any of these organizations, they have not sponsored me in any way to mention this, but if you want to make a difference in another way here are people who do important things and always need support, in no particular order:

Médecins Sans Frontière

Human Rights Campaign

Human Rights Watch

All Out

International Refugee Assistance Project

Planned Parenthood

Amnesty International